The most common symptom is blood in the urine (hematuria), which is present in up to 65 percent of cases. Abdominal pain is found in 40 percent of patients and an abdominal mass in 35 percent. Other common symptoms include anemia , bone pain, unexplained weight loss, low-grade fever, general weakness or loss of energy and loss of appetite.
Unusual symptoms may include hypercalcemia (high blood calcium), high blood pressure, abnormal liver tests or too many red cells in the blood (polycythemia). These symptoms develop because renal tumors can produce substances that indirectly affect other organs, producing conditions called paraneoplastic syndromes.
